Imaging the effective networks associated with cortical function through intracranial high-frequency stimulations
*Andrei Barborica, *Irina Oane, Cristian Donos, Andrei Daneasa, Felicia Mihai, Constantin Pistol, Adriana Roceanu, *Ioana Mindruta

This folder contains the folowing data and scripts required to reproduce the results presented in the paper.

SOFTWARE:
|-FreeSurfer - all the files below are accesed using Matlab to create a 3D model of the brain
  |-fsaverage
    |-Brain Atlases - file that help us to plot different
      |-BrainMesh_ICBM152.mat - used to create a default brain surface, based on MNI152 atlas; all patients below have the MNI coordinates normalized to this surface
    |-label - labels used to create the HCPPMP1 parcellation of the brain surface
      |-lh.HCPMMP1.annot 
      |-rh.HCPMMP1.annot
    |- surf
      |-lh.fsaverage_sym.sphere.reg - used to load the average sphere projection
      |-lh.inflated - Used in APStimPopulation.m to load the fsaverage inflatd surface for the left hemisphere
      |-lh.pial - Used in APStimPopulation.m to smooth th brain surface
      |-lh.sphere.reg- used in APStimPopulation.m to load the sphere projection
      |-rh.fsaverage_sym.sphere.reg - used to load the average sphere projection
      |-rh.inflated - used in APStimPopulation.m to load the fsaverage inflated surface for the right hemisphere
      |-rh.pial - Used in APStim.m to smooth th brain surface
      |-rh.sphere.reg - used in APStim.m to load the sphere projection
|-Matlab - all the files below can be accesed with Matlab to analyze the signals.
  |-APSpectrum.m - creating the plots for the alternating polarity singnals and its frequency spectrum
  |-APStim.m - processing the 43Hz/50Hz alternation polarity stimulation data
  |-APStimPopulation.m - performs the analysis of the HFS symptom's network at the population level
  |-APStimSimulation.m - performs a comparison of the time-domin (TD) vs frequency-domain (FD) analysis on stimulated signals
  |-CompareTreshholds.m - compares the thresholds for evoking clinical symptoms during hight-frequency stimulations
  |-NicoletFile.m - reading the Nicolet files (.e)
  |-tdfd.m - compares results of time-domain and frequency-domain analysis for the responses to 43Hz/50Hz stimulations
|- Toolbox - all the toolboxed that out Matlab algorithms use to read, analyze and plot our data.
 

DATA:
|-Patient1
  |-FreeSurfer
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files 
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-Nicolet
    |-Raw data - Nicolet files (.e), 50Hz stimulations, can be opened with NicoletFiles.m in Matlab
  |-SEEG 65.xls
|-Patient2
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg  - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-Nicolet
    |-Raw data - Nicolet files (.e), 50Hz stimulations, can be opened with NicoletFiles.m in Matlab
  |-SEEG 66.xls
|-Patient3
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg  - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-Nicolet
    |-Raw data - Nicolet files (.e), 50Hz stimulations, can be opened with NicoletFiles.m in Matlab
  |-SEEG 67.xls
|-Patient4
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
    |-mri
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf - MRI files
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-Nicolet
    |-Raw data - Nicolet files (.e), 50Hz stimulations, can be opened with NicoletFiles.m in Matlab
  |-SEEG 68.xls
|-Patient5
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 50Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 70.xls
|-Patient6
  |-FreeSurfer
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 50Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 71.xls
|-Patient7
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 50Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 72.xls
|-Patient8 
  |-FreeSurfer - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
    |-label
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 50Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 73.xls
|-Patient9
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data -50Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 75.xls
|-Patient10
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-Nicolet
    |-Raw data - 50Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 76.xls
|-Patient11
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 77.xls
|-Patient12
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pialused in ApStim.m to load the smoothed surface
     |-lh.smoothed.pialused in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pialused in ApStim.m to load the smoothed surface
     |-rh.smoothed.pialused in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 80.xls
|-Patient13
  |-FreeSurfer
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 83.xls
|-Patient14 
  |-FreeSurfer - all the files below can be accesed with Matlab to create the 3D model of the brain of this patient
    |-label- all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf- MRI files
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 84.xls
|-Patient15
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 85.xls
|-Patient16
  |-FreeSurfer
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri- MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 86.xls
|-Patient17 
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 87.xls
|-Patient18
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 88.xls
|-Patient19
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 89.xls
|-Patient20 
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg  - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 92.xls
|-Patient21
  |-FreeSurfer 
    |-label- all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 96.xls
|-Patient22
  |-FreeSurfer - all the files below can be accesed with Matlab to create the 3D model of the brain of this patient
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 97.xls
|-Patient23
  |-FreeSurfer 
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 98.xls
|-Patient24
  |-FreeSurfer
    |-label- all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI files
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 99.xls
|-Patient25
  |-FreeSurfer - all the files below can be accesed with Matlab to create the 3D model of the brain of this patient
    |-label- all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri MRI file
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial  - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 100.xls
|-Patient26
  |-FreeSurfer
    |-label - all of the labels below are used in APStim to create different types of parcellation of the brain structure, by faces and vertices, of th patient
      |-lh.aparc.a2009.annot
      |-lh.aparc.annot
      |-lh.aparc.DKTatlas.annot
      |-rh.aparc.a2009.annot
      |-rh.aparc.annot
      |-rh.aparc.DKTatlas.annot
    |-mri - MRI file
      |-orig
        |-001.mgh
        |-001.mgz
   |-surf
     |-lh.pial - used in ApStim.m to load the smoothed surface
     |-lh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-lh.sphere.reg - used in ApStim..m to load the spherical projection
     |-rh.pial  - used in ApStim.m to load the smoothed surface
     |-rh.smoothed.pial  - used in ApStim.m to load the smoothed surface
     |-rh.sphere.reg - used in ApStim..m to load the spherical projection
  |-ADES
    |-Raw data - 43Hz stimulations in AnyWave (*.ades) format.The ADES format specification is available at https://meg.univ-amu.fr/wiki/AnyWave:ADES 
  |-SEEG 101.xls

SUPPORTING TABLES: - all the xls and xlsx files below can be opened with Microsoft Office Excel
|-FunctionalStimulations.xlsx - Responses of the high frequency stimulations for each pair of contacts stimulated
|-Patients.xlsx - Informations about the epilepsy type, lateralizations, bad contact and artefacted stimulations
|-SPESData.xls - informations about the location of each electrode in the patients brain, location and contacts coordinates
|-web.config