Networks underlying human cortical function revealed by intracranial electrical stimulation

Romanian Government UEFISCDI
research grant PN-III-P4-ID-PCE-2020-0935

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Online atlas:

http://epi.fizica.unibuc.ro/symnet/

Papers:

Barborica A, Mindruta I, López-Madrona VJ, Alario FX, Trébuchon A, Donos C, Oane I, Pistol C, Mihai F, Bénar CG. Studying memory processes at different levels with simultaneous depth and surface EEG recordings. Front Hum Neurosci. 2023 Apr 4;17:1154038. https://doi.org/10.3389/fnhum.2023.1154038.
Bratu IF, Nica AE, Oane I, Daneasa A, Stoica S, Barborica A, Mindruta I. Musicogenic seizures in temporal lobe epilepsy: Case reports based on ictal source localization analysis. Front Neurol. 2023 Feb 20;14:1072075. https://doi.org/10.3389/fneur.2023.1072075.
Oane I, Barborica A, Mindruta I. Cingulate Cortex: Anatomy, Structural and Functional Connectivity. J Clin Neurophysiol. 2023 Mar 16. https://doi.org/10.1097/WNP.0000000000000970.
Oane I, Barborica A, Daneasa A, Maliia MD, Ciurea J, Stoica S, Dabu A, Bratu F, Lentoiu C, Mindruta I. Organization of the epileptogenic zone and signal analysis at seizure onset in patients with drug-resistant epilepsy due to focal cortical dysplasia with mTOR pathway gene mutations-An SEEG study. Epilepsia Open. 2023 Aug 13. https://doi.org/10.1002/epi4.12810.
Barborica A, Oane I, Donos C, Daneasa A, Mihai F, Pistol C, Dabu A, Roceanu A, Mindruta I. Imaging the effective networks associated with cortical function through intracranial high-frequency stimulation. Hum Brain Mapp. 2022 Apr 1;43(5):1657-1675. https://doi.org/10.1002/hbm.25749.
Donos C, Blidarescu B, Pistol C, Oane I, Mindruta I, Barborica A. A comparison of uni- and multi-variate methods for identifying brain networks activated by cognitive tasks using intracranial EEG. Front Neurosci. 2022 Sep 26;16:946240. https://doi.org/10.3389/fnins.2022.946240.
Lentoiu C, Oane I, Barborica A, Donos C, Pistol C, Daneasa A, Bratu FI, Mindruta I. Motor and emotional facial features in parietal lobe seizures: an ictal functional connectivity study using SEEG. Epileptic Disord. 2022 Oct 1;24(5):838-846. English. https://doi.org/10.1684/epd.2022.1456.
Bratu, F.-I., Oane, I., Barborica, A., Donos, C., Pistol, C., Daneasa, A., Lentoiu, C., Mindruta, I., 2021. Network of autoscopic hallucinations elicited by intracerebral stimulations of periventricular nodular heterotopia: An SEEG study. Cortex 145, 285-294. https://doi.org/10.1016/J.CORTEX.2021.08.018
Barborica A, Mindruta I, Sheybani L, Spinelli L, Oane I, Pistol C, Donos C, López-Madrona VJ, Vulliemoz S, Bénar CG. Extracting seizure onset from surface EEG with independent component analysis: Insights from simultaneous scalp and intracerebral EEG. Neuroimage Clin. 2021 Sep 29;32:102838. doi: 10.1016/j.nicl.2021.102838.
Pistol C, Daneasa A, Ciurea J, Rasina A, Barborica A, Oane I, Mindruta I. Accuracy and Safety of Customized Stereotactic Fixtures for Stereoelectroencephalography in Pediatric Patients, 2021. Stereotact Funct Neurosurg. 99(1):17-24. doi: 10.1159/000510063.

Conferences:

2023

Andrei Barborica, Ioana Mindruta, Christian G. Benar Simultaneous EEG-SEEG during electrical cortical stimulation, 18th European Congress of Clinical Neurophysiology, May 9-12, Marseille, France.
Cristina Ghita, Irina Oane, Camelia Lentoiu, Flavius Bratu, Ioana Mindruta - Cum interpretam clinic informa?ia examenului EEG?. Al XXI-lea Congres al Societa?ii de Neurologie din România, 7-9 June 2023, Sinaia, Romania
Irina Oane, Camelia Lentoiu, Flavius Bratu, Cristina Ghita, Constantin Pistol, Felicia Mihai, Laurentiu Tofan, Andrei Barborica, Ioana Mindruta. Multiscale EEG and ictal semiology correlates. 14-th ASNER Summer School, 7-9 July 2023, Eforie Nord, Romania.
Laurentiu Tofan, Felicia Mihai, Irina Oane, Ana-Maria Zagrean, Andrei Barborica, Ioana Mindruta - Exploration of the brain connectivity in patients with pharmacoresistant epilepsy and visual hallucinations. 3rd International Conference on Neuroscience, Neuroinformatics, Neurotechnology and Neuro-Psycho-Pharmacology ICON4N, 26-28 October 2023, Bucharest, Romania

2022

Andrei Barborica, Ioana Mindruta, Christian G. Benar, Irina Oane, Felicia Mihai, Cristian Donos, Constantin Pistol. Intracranial Stimulations as Ground Truth for Testing Visibility of Deep High-Frequency EEG Sources - A Simultaneous Scalp-SEEG Study, American Epilepsy Society (AES) Anual Meeting 2022, Dec 2-6, Nashville, USA.
Irina Oane, Andrei Barborica, Felicia Mihai, Andrei Daneasa, Flavius Bratu, Camelia Lentoiu, Constantin Pistol, Cristian Donos, Ioana Mindruta. Network of Insular Physiologic and Epileptogenic Signs and Symptoms, American Epilepsy Society (AES) Anual Meeting 2022, Dec 2-6, Nashville, USA.
Cristian Donos, Bogdan Blidarescu, Irina Oane, Constantin Pistol, Ioana Mindruta, Andrei Barborica. Search light analysis for intracranial EEG recordings, FENS Forum, 9-13 July 2022, Paris, France.
Andrei Barborica, Ioana Mindruta, Irina Oane, Felicia Mihai, Cristian Donos, Constantin Pistol. Simultaneous scalp-intracranial EEG recordings in patients with drug-resistant epilepsy as a means to validate source localization algorithms, 13th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology, 21-23 Oct, 2022, Bucharest, Romania.
Ionu?-Flavius Bratu, Andrei Barborica, Irina Oane, Camelia Lentoiu, Felicia Mihai, Cristian Donos, Constantin Pistol, Ioana Mindruta. Gray matter heterotopias - is there something more than meets the eye on scalp EEG traces? - a simultaneous scalp EEG-stereo-EEG study, 32nd International Congress of Clinical Neurophysiology, Sep 04-08, 2022, Geneva, Switzerland.
Andrei Barborica, Ioana Mindruta, Irina Oane, Cristian Donos, Felicia Mihai, Constantin Pistol. Validation of EEG source localization algorithms through simultaneous scalp-intracranial EEG recordings in patients with drug-resistant epilepsy, SNN, SRF and Brain Day 2022, Sep 29 - Oct 1, 2022, Bucharest, Romania.

2021

Andrei Barborica, Ioana Mindruta, Christian G. Benar, Serge Vulliemoz, Irina Oane, Felicia Mihai, Cristian Donos, Constantin Pistol. What Scalp Recordings Tell Us About Intracranial Stimulations? A Simultaneous Scalp-SEEG Study, American Epilepsy Society (AES) Anual Meeting 2021, Dec 3-7, Chicago, USA.
Ioana Mindruta, Irina Oane, Flavius Bratu, Camelia Lentoiu, Felicia Mihai, Cristian Donos, Andrei Barborica. Insular-Cingulate Resting State and Symptom Related Connectivity Interplay in Patients with Drug-Resistant Epilepsy, American Epilepsy Society (AES) Anual Meeting 2021, Dec 3-7, Chicago, USA.
Irina Oane, Andrei Barborica, Cristian Donos, Constantin Pistol, Andrei Daneasa, Camelia Lentoiu, Flavius Bratu, Ioana Mindruta. Reflex seizures and the brain networks involved. 12th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER), 9-10 July 2021, Eforie, Romania
Irina Oane, Andrei Barborica, Cristian Donos, Andrei Daneasa, Flavius Bratu, Camelia Lentoiu, Constantin Pistol, Bogdan Blidarescu, Aurelia Dabu, Cornel Tudor, Ioana Mindruta. Rolul stimularii cerebrale directe cu electrozi intacraniani in explorarea epilepsiei farmacorezistente. Al XIX-lea Congres National al Societatii de Neurologie din Romania. 16-19 Noiembrie 2021, Congres Virtual.

Progress Reports: